Hormone Therapy

Estradiol Cream

CategoryHormone Therapy

Estradiol 0.01% vaginal cream · 42.5 g

Starting at$149.00 / month
Estradiol Cream
Clinician
reviewed
Free
shipping
Licensed
US pharmacy

Hormone Therapy

Local support, where it's needed.

As estrogen declines through perimenopause and menopause, vaginal and vulvar tissue can change.

Estradiol 0.01% vaginal cream is applied locally to the vaginal area, with initial and maintenance dosing directed by your clinician.

Select treatment cycle

Total due now

$447.00

3-month supply · $149.00/month

Prescription products require review by a licensed physician. After checkout you'll receive member portal access to complete your medical intake form. A physician reviews it and, if you qualify, your medication is dispensed. Dosing is determined by your provider during review.

Replace what your body is making less of.

As estrogen declines through perimenopause and menopause, vaginal and vulvar tissue can become thinner, drier and less elastic. Estradiol 0.01% vaginal cream is applied locally to the vaginal area to replenish estrogen in that tissue. Your clinician directs an initial phase and a maintenance phase based on your symptoms and response.

At a glance

0.01%

Estradiol vaginal cream, 42.5 g

Local

Applied to the vaginal area

Personalized

Selected around symptoms + history

Clinician guided

Reviewed as your needs evolve

A better place to start

69 biomarkers. $79. On purpose.

We don't believe meaningful insight into your health should feel out of reach. Essentials gives you a broad baseline across key areas of your biology for $79.

Not as a promotion. As a principle.

A closer look

Hormones move. The whole picture matters.

During perimenopause, estrogen can fluctuate considerably from one day to the next. A single estradiol result doesn't always explain how you feel — and there isn't one universal estrogen number every woman should be trying to reach.

Symptoms, cycle changes, health history and treatment response often provide the most important context.

Labs become useful when your provider needs to understand what else may be contributing or build a broader picture of your health through the menopause transition.

Explore Labs

Estradiol + FSH

May provide additional context when menopausal status is uncertain or symptoms occur earlier than expected.

Thyroid

Thyroid changes can overlap with menopause symptoms, including fatigue, temperature changes, mood shifts and brain fog.

CBC + Iron

Especially relevant when heavy or irregular bleeding and fatigue are part of the picture.

Metabolic + Lipid Markers

Help build a broader view of cardiometabolic health as your body changes through midlife.

Vitamin D + Bone Health

May be considered as part of a broader assessment of bone health based on age, history and individual risk.