Estradiol Cream
Estradiol 0.01% vaginal cream · 42.5 g

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Hormone Therapy
Local support, where it's needed.
As estrogen declines through perimenopause and menopause, vaginal and vulvar tissue can change.
Estradiol 0.01% vaginal cream is applied locally to the vaginal area, with initial and maintenance dosing directed by your clinician.
Choose your medication
Select treatment cycle
Total due now
$447.00
3-month supply · $149.00/month
Prescription products require review by a licensed physician. After checkout you'll receive member portal access to complete your medical intake form. A physician reviews it and, if you qualify, your medication is dispensed. Dosing is determined by your provider during review.
At a glance
0.01%
Estradiol vaginal cream, 42.5 g
Local
Applied to the vaginal area
Personalized
Selected around symptoms + history
Clinician guided
Reviewed as your needs evolve
69 biomarkers. $79. On purpose.
We don't believe meaningful insight into your health should feel out of reach. Essentials gives you a broad baseline across key areas of your biology for $79.
Not as a promotion. As a principle.
Hormones move. The whole picture matters.
During perimenopause, estrogen can fluctuate considerably from one day to the next. A single estradiol result doesn't always explain how you feel — and there isn't one universal estrogen number every woman should be trying to reach.
Symptoms, cycle changes, health history and treatment response often provide the most important context.
Labs become useful when your provider needs to understand what else may be contributing or build a broader picture of your health through the menopause transition.
Explore LabsEstradiol + FSH
May provide additional context when menopausal status is uncertain or symptoms occur earlier than expected.
Thyroid
Thyroid changes can overlap with menopause symptoms, including fatigue, temperature changes, mood shifts and brain fog.
CBC + Iron
Especially relevant when heavy or irregular bleeding and fatigue are part of the picture.
Metabolic + Lipid Markers
Help build a broader view of cardiometabolic health as your body changes through midlife.
Vitamin D + Bone Health
May be considered as part of a broader assessment of bone health based on age, history and individual risk.
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