Estradiol Cream
30 g topical tube
Hormone Therapy
Hormone support, through the skin.
Estrogen influences systems throughout the female body, from temperature regulation and sleep to bone and reproductive tissue.
As estrogen becomes less predictable through perimenopause and declines with menopause, the shift can show up in ways that are hard to ignore.
Transdermal estrogen cream delivers systemic hormone support through the skin as part of a personalized, clinician-guided hormone plan.
Select treatment cycle
Subscription requiredTotal due now
$80.00
$80.00 per month · 1 month
Prescription products require review by a licensed physician. After checkout you'll receive member portal access to complete your medical intake form. A physician reviews it and, if you qualify, your medication is dispensed. Dosing is determined by your provider during review.
At a glance
Topical
Applied through the skin
Systemic
Estrogen support throughout the body
Personalized
Selected around symptoms + history
Clinician guided
Reviewed as your needs evolve
73 biomarkers. $59. On purpose.
We don't believe meaningful insight into your health should feel out of reach. Essentials gives you a broad baseline across key areas of your biology for $59.
Not as a promotion. As a principle.
Hormones move. The whole picture matters.
During perimenopause, estrogen can fluctuate considerably from one day to the next. A single estradiol result doesn't always explain how you feel — and there isn't one universal estrogen number every woman should be trying to reach.
Symptoms, cycle changes, health history and treatment response often provide the most important context.
Labs become useful when your provider needs to understand what else may be contributing or build a broader picture of your health through the menopause transition.
Explore LabsEstradiol + FSH
May provide additional context when menopausal status is uncertain or symptoms occur earlier than expected.
Thyroid
Thyroid changes can overlap with menopause symptoms, including fatigue, temperature changes, mood shifts and brain fog.
CBC + Iron
Especially relevant when heavy or irregular bleeding and fatigue are part of the picture.
Metabolic + Lipid Markers
Help build a broader view of cardiometabolic health as your body changes through midlife.
Vitamin D + Bone Health
May be considered as part of a broader assessment of bone health based on age, history and individual risk.
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