Longevity & Cognition

Sirolimus (Rapamycin)

CategoryLongevity & Cognition
Starting at$225 / month
Sirolimus (Rapamycin)
Clinicianreviewed
Freeshipping
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Longevity & Cognition

Healthy cells know when to grow — and when to maintain.

Sirolimus acts on mTOR, one of the body's central nutrient-sensing pathways involved in cellular growth, metabolism and recycling.

In low, intermittent dosing, sirolimus is being studied for its ability to modulate this pathway and what that may mean for healthy aging.

A research-informed approach for people thinking about longevity at the cellular level.

Total due now

$225.00

1 month · per month

Prescription products require review by a licensed physician. After checkout you'll receive member portal access to complete your medical intake form. A physician reviews it and, if you qualify, your medication is dispensed. Dosing is determined by your provider during review.

Dial down the growth signal.

mTOR helps cells respond to nutrients, energy availability and growth signals. When mTOR activity is high, the body prioritizes growth and protein synthesis. Sirolimus temporarily reduces mTOR signaling. That shift is associated with cellular maintenance pathways, including autophagy — the process cells use to break down and recycle damaged or unnecessary components. Researchers are studying whether strategically modulating this pathway may influence aspects of healthspan and age-related biology in humans.

At a glance

Weekly

Intermittent dosing

mTOR

Targets a major nutrient-sensing pathway

Long-view

Rooted in aging biology

Clinician guided

Labs + response monitored over time

A better place to start

73 biomarkers. $59. On purpose.

We don't believe meaningful insight into your health should feel out of reach. Essentials gives you a broad baseline across key areas of your biology for $59.

Not as a promotion. As a principle.

A closer look

Longevity doesn't come with one score.

There isn't a blood test that tells you whether your mTOR pathway is “optimized.”

With sirolimus, labs serve a different and important purpose: helping your provider understand your baseline health and monitor how your body is tolerating treatment over time.

Explore Labs

CBC

Monitors white blood cells, red blood cells and platelets, which can be affected by sirolimus.

Lipid Panel + ApoB

Sirolimus can affect cholesterol and triglycerides, making lipid monitoring particularly important.

Glucose + Hemoglobin A1c

Provides insight into glucose regulation and metabolic health during treatment.

Kidney + Liver Function

Creatinine, liver enzymes and other metabolic markers help provide an ongoing safety picture.

Urinalysis / Urine Protein

May be considered because sirolimus can affect kidney-related markers, including urinary protein.

Additional Monitoring

Your provider may recommend additional testing based on dose, medications, health history and individual response.