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Longevity & Cognition

Metformin XR 500

CategoryLongevity & Cognition
Starting at$25 / month
Metformin XR 500
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Longevity & Cognition

Metabolic health compounds over time.

How your body handles glucose and responds to insulin shapes far more than a number on a lab report.

Metformin is one of the most studied medications in metabolic health. It works primarily by reducing excess glucose production by the liver and improving the way the body manages glucose.

Its long history in metabolic medicine — and emerging research into aging biology — has also made metformin an important part of the longevity conversation.

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$75.00

3 months · per month

Prescription products require review by a licensed physician. After checkout you'll receive member portal access to complete your medical intake form. A physician reviews it and, if you qualify, your medication is dispensed. Dosing is determined by your provider during review.

Help your metabolism work with less friction.

Your liver is constantly helping manage the amount of glucose circulating in your blood — including by producing glucose between meals. Metformin helps reduce excess hepatic glucose production and improves glucose regulation without directly stimulating the pancreas to produce more insulin. That makes it particularly relevant when blood sugar and insulin regulation are beginning to move in the wrong direction. Beyond glucose control, researchers continue to study how metformin interacts with cellular-energy sensing, mitochondrial metabolism and other pathways connected to aging biology.

At a glance

Daily

Extended-release tablet

Metabolic

Supports glucose regulation

Established

Decades of clinical use

Research-informed

Studied across metabolism + aging biology

A better place to start

73 biomarkers. $59. On purpose.

We don't believe meaningful insight into your health should feel out of reach. Essentials gives you a broad baseline across key areas of your biology for $59.

Not as a promotion. As a principle.

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A closer look

Metabolic health leaves a trail.

You don't have to wait for diabetes to start paying attention to glucose regulation.

Small shifts in fasting glucose, A1c, insulin and other metabolic markers can create a much clearer picture of where your metabolism is heading.

With metformin, labs help identify who may benefit, establish a baseline and monitor both response and safety over time.

Explore Labs

Glucose + Hemoglobin A1c

Show how your body is managing blood sugar today and over the previous several months.

Fasting Insulin

Can provide additional context around insulin regulation when clinically useful.

Kidney Function / eGFR

Essential before starting metformin and monitored over time because kidney function affects how the medication is cleared.

Vitamin B12

Metformin can lower B12 levels with ongoing use, making periodic monitoring particularly important.

Lipid Panel + ApoB

Help build a broader picture of cardiometabolic health and risk.

Comprehensive Metabolic Panel

Provides additional context around kidney function, liver markers, electrolytes and glucose.

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